miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase
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منابع مشابه
miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase
Cardiomyocyte apoptosis is initiated by various cellular insults and accumulated cardiomyocyte apoptosis leads to the pathogenesis of heart failure. Excessive reactive oxygen species (ROS) provoke apoptotic cascades. Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme that converts cellular ROS into harmless products. In this study, we demonstrate that MnSOD is down-regula...
متن کاملManganese Superoxide Dismutase (MnSOD)
2 Introduction 3 Phylogenetic distribution and subcellular localization 3 Kinetics and mechanism 3 Molecular and chemical structure 5 Biological significance 8 Summary 9 References 10 Abstract Manganese superoxide dismutase (MnSOD) is the primary antioxidant enzyme that protects cells from oxidative stress by catalyzing dismutation of superoxide (O2 ) to hydrogen peroxide and oxygen in the mito...
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ژورنال
عنوان ژورنال: Molecules and Cells
سال: 2017
ISSN: 1016-8478,0219-1032
DOI: 10.14348/molcells.2017.0012